Franz Cells
This diffusion cell is the most common of all Franz Cells. It is a Jacketed Franz Cell with a 9mm orifice diameter, flat ground joint, and 5ml receptor volume. It is the de facto standard for working with human skin and may be used with any membrane 4mm or less in thickness.

PermeGear vertical glass diffusion cells are the classic Franz Cells. Standard orifice diameters are 5mm, 7mm, 9mm, 11.28mm, 15mm, 20mm and 25mm, other diameters are custom. The word “orifice” as it refers to a Franz Cell is the area at the top of the receptor chamber that is exposed to the membrane or device through which transport or permeation is being studied. Corresponding volumes from 5ml to 20ml are standard. Clamping is achieved through o-ring joints, flat ground (ground o-ring) joints. We manufacture our own clamps for the most popular Franz Cell models. Our clamps are all stainless steel and are much easier to use than clamps from other suppliers.
Dimensions of Standard Franz Cells
Standard 5mm Jacketed or Unjacketed Franz Cell Specifications
|
Flat Ground Joint
|
Flat Flange Joint
|
0-ring Joint
|
Joint I.D.
|
5mm
|
N/A
|
5mm
|
Joint O.D.
|
19mm
|
N/A
|
19mm
|
Receptor Volume
|
5ml
|
N/A
|
5ml
|
Orifice Area
|
.20cm2
|
N/A
|
.20cm2
|
Jacket Diameter
|
30mm
|
N/A
|
30mm
|
Standard 7mm Jacketed or Unjacketed Franz Cell Specifications
|
Flat ground Joint
|
Flat Flange Joint
|
Q-ring Joint
|
Joint 1.D.
|
7mm
|
N/A
|
7mm
|
Joint O.D.
|
22mm
|
N/A
|
22mm
|
Receptor Volume
|
5ml
|
N/A
|
5ml
|
Orifice Area
|
.38cm2
|
N/A
|
.38cm2
|
Jacket Diameter
|
30mm
|
N/A
|
30mm
|
Standard 9mm Jacketed or Unjacketed Franz Cell Specifications
|
Flat Ground Joint
|
Flat Flange Joint
|
0-ring Joint
|
Joint 1.D.
|
9mm
|
9mm
|
5mm
|
Joint O.D.
|
25mm
|
27mm
|
19mm
|
Receptor Volume
|
5ml
|
5ml
|
5ml
|
Orifice Area
|
.64cm2
|
.64cm2
|
.64cm2
|
Jacket Diameter
|
30mm
|
30mm
|
30mm
|
Standard 11.28mm Jacketed or Unjacketed Franz Cell Specifications
|
Flat Ground Joint
|
Flat Flange Joint
|
0-ring Joint
|
|
|
Joint I.D.
|
11.28mm
|
11.28mm
|
11.28mm
|
|
Joint 0.0.
|
28mm
|
30mm
|
28mm
|
|
Receptor Volume
|
8ml
|
8ml
|
8ml
|
|
Orifice Area
|
1.00cm2
|
1.00cm2
|
1.00cm2
|
|
Jacket Diameter
|
30mm
|
30mm
|
30mm
|
|
Standard 15mm Jacketed or Unjacketed Franz Cell Specifications
|
Flat Ground Joint
|
Flat Flange Joint
|
0-ring Joint
|
Joint I.D.
|
15mm
|
15mm
|
15mm
|
Joint O.D.
|
30mm
|
35mm
|
30mm
|
Receptor Volume
|
7.5 or 12ml
|
7.5 or 12ml
|
7.5 or 12ml
|
Orifice Area
|
1.77cm2
|
1.77cm2
|
1.77cm2
|
Jacket Diameter
|
30mm
|
30mm
|
30mm
|
Standard 20mm Jacketed or Unjacketed Franz Cell Specifications
|
Flat Ground Joint
|
Flat Flange Joint
|
0-ring Joint
|
Joint 1.D.
|
20mm
|
20mm
|
20mm
|
Joint O.D.
|
37mm
|
43mm
|
36mm
|
Receptor Volume
|
15ml
|
15ml
|
15ml
|
Orifice Area
|
3.14cm2
|
3.14cm2
|
3.14cm2
|
|
Jacket Diameter
|
30mm
|
30mm
|
30mm
|
Standard 25mm Jacketed or Unjacketed Franz Cell Specifications
|
Flat Ground Joint
|
Flat Flange Joint
|
0-ring Joint
|
Joint 1.D.
|
25mm
|
25mm
|
25mm
|
Joint 0.0.
|
44mm
|
50mm
|
44mm
|
Receptor Volume
|
20ml
|
20ml
|
20ml
|
Orifice Area
|
4.91cm2
|
4.91cm2
|
4.91cm2
|
Jacket Diameter
|
30mm
|
30mm
|
30mm
|
Standard Spherical Joint Jacketed or Unjacketed Franz Cell Specifications
Orifice in Sphere
|
Two Sizes Available
|
5mm
|
9mm
|
Sphere Diameter
|
12mm
|
18mm
|
Receptor Volume
|
5ml
|
5ml
|
Orifice Area
|
.20cm2
|
.64cm2
|
Jacket Diameter
|
30mm
|
30mm
|
PermeGear V-Series Stirrers are made for use with our jacketed Franz cells. They have aluminum supply manifolds mounted toward the rear that connect to a water bath and pump, or heater/recirculator.
All V-Series stirrers run at 120v/60hz/6COrpm or 230v/50hz/500rpm.
V series Stirrers
PermeGear's V-Series Manual Diffusion Systems are an apparatus employing Franz Cells for carrying out in vitro release testing (IVRT) and in vitro permeation testing (IVPT). The systems enable a researcher to measure the release or permeation of a compound into or through membranes.
Franz Cells in the V-Senes Manual Diffusion Systems are firmly held directly above individual stirrers and surrounded with a "Jacket" through which heated water is circulated The result is a safer and more secure apparatus with better ability to control experimental variables.


V3B stirrer V6-CB stirrer V9-CA stirrer


V9-CB stirrer V6-CA stirrer