Analytical

Franz Cells

This diffusion cell is the most common of all Franz  Cells.  It is a Jacketed Franz Cell with a 9mm orifice diameter, flat ground joint, and 5ml receptor volume.  It is the de facto standard for working with human skin and may be used with any membrane 4mm or less in thickness.

 

 

PermeGear vertical glass diffusion cells are the classic Franz Cells. Standard orifice diameters are 5mm, 7mm, 9mm, 11.28mm, 15mm, 20mm and 25mm, other diameters are custom. The word “orifice” as it refers to a Franz Cell is the area at the top of the receptor chamber that is exposed to the membrane or device through which transport or permeation is being studied. Corresponding volumes from 5ml to 20ml are standard. Clamping is achieved through o-ring joints, flat ground (ground o-ring) joints. We manufacture our own clamps for the most popular Franz Cell models. Our clamps are all stainless steel and are much easier to use than clamps from other suppliers.

 

Dimensions of Standard Franz Cells

Standard 5mm Jacketed or Unjacketed Franz Cell Specifications

 

Flat Ground Joint

Flat Flange Joint

0-ring Joint

Joint I.D.

5mm

N/A

5mm

Joint O.D.

19mm

N/A

19mm

Receptor Volume

5ml

N/A

5ml

Orifice Area

.20cm2

N/A

.20cm2

Jacket Diameter

30mm

N/A

30mm

 

Standard 7mm Jacketed or Unjacketed Franz Cell Specifications

 

 

Flat ground Joint

Flat Flange Joint

Q-ring Joint

Joint 1.D.

7mm

N/A

7mm

Joint O.D.

22mm

N/A

22mm

Receptor Volume

5ml

N/A

5ml

Orifice Area

.38cm2

N/A

.38cm2

Jacket Diameter

30mm

N/A

30mm

 

Standard 9mm Jacketed or Unjacketed Franz Cell Specifications

 

 

Flat Ground Joint

Flat Flange Joint

0-ring Joint

Joint 1.D.

9mm

9mm

5mm

Joint O.D.

25mm

27mm

19mm

Receptor Volume

5ml

5ml

5ml

Orifice Area

.64cm2

.64cm2

.64cm2

Jacket Diameter

30mm

30mm

30mm

 

 

Standard 11.28mm Jacketed or Unjacketed Franz Cell Specifications

 

 

Flat Ground Joint

Flat Flange Joint

0-ring Joint

 
 

Joint I.D.

11.28mm

11.28mm

11.28mm

 

Joint 0.0.

28mm

30mm

28mm

 

Receptor Volume

8ml

8ml

8ml

 

Orifice Area

1.00cm2

1.00cm2

1.00cm2

 

Jacket Diameter

30mm

30mm

30mm

 

 

Standard 15mm Jacketed or Unjacketed Franz Cell Specifications

 

 

Flat Ground Joint

Flat Flange Joint

0-rinJoint

Joint I.D.

15mm

15mm

15mm

Joint O.D.

30mm

35mm

30mm

Receptor Volume

7.5 or 12ml

7.5 or 12ml

7.5 or 12ml

Orifice Area

1.77cm2

1.77cm2

1.77cm2

Jacket Diameter

30mm

30mm

30mm

 

 

Standard 20mm Jacketed or Unjacketed Franz Cell Specifications

 

 

Flat Ground Joint

Flat Flange Joint

0-ring Joint

Joint 1.D.

20mm

20mm

20mm

Joint O.D.

37mm

43mm

36mm

Receptor Volume

15ml

15ml

15ml

Orifice Area

3.14cm2

3.14cm2

3.14cm2

 

Jacket Diameter

30mm

30mm

30mm

 

Standard 25mm Jacketed or Unjacketed Franz Cell Specifications

 

 

Flat Ground Joint

Flat Flange Joint

0-ring Joint

Joint 1.D.

25mm

25mm

25mm

Joint 0.0.

44mm

50mm

44mm

Receptor Volume

20ml

20ml

20ml

Orifice Area

4.91cm2

4.91cm2

4.91cm2

Jacket Diameter

30mm

30mm

30mm

 

 

Standard Spherical Joint Jacketed or Unjacketed Franz Cell Specifications

 

Orifice in Sphere

Two Sizes Available

5mm

9mm

Sphere Diameter

12mm

18mm

Receptor Volume

5ml

5ml

Orifice Area

.20cm2

.64cm2

Jacket Diameter

30mm

30mm

 

 

PermeGear V-Series Stirrers are made for use with our jacketed Franz cells. They have aluminum supply manifolds mounted toward the rear that connect to a water bath and pump, or heater/recirculator.

All V-Series stirrers run at 120v/60hz/6COrpm or 230v/50hz/500rpm.

 

V series Stirrers

PermeGear's V-Series Manual Diffusion Systems are an apparatus employing Franz Cells for carrying out in vitro release testing (IVRT) and in vitro permeation testing (IVPT). The systems enable a researcher to measure the release or permeation of a compound into or through membranes.

 

Franz Cells in the V-Senes Manual Diffusion Systems are firmly held directly above individual stirrers and surrounded with a "Jacket" through which heated water is circulated The result is a safer and more secure apparatus with better ability to control experimental variables.

 

                      V3B stirrer                                                                  V6-CB stirrer                                                                                    V9-CA stirrer

 

                                              V9-CB stirrer                                                                                         V6-CA stirrer

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